Sociotype is a concept that allows a more comprehensive understanding about biosociology of undiagnosed rare diseases (URD). Sociotype is related to a genotype and a phenotype and it is an expression of the individual life world in society. In this paper, semiotic and hermeneutic analysis of papers published and selected about URD is developed. Te perspective followed in this research is aligned with the works of Barbieri and Peirce. Papers with the most social content have been selected and those with (...) a more biomedical content have been rejected. Te semiotics analysis has been divided in genotypic, phenotypic and sociotypic, and related to the hermeneutical perspective. It has been possible to understand the basis of semiotics elements of URD. Te general conclusion is that URD is a particular sociotype with a determined set of social characteristics. Tis paper opens research on the biosemiotic and hermeneutic perspective about URD. (shrink)

Tras reseñar diferentes sociólogos que han destacado la importancia de la originalidad para la creatividad, este artículo tiene como objetivo analizar el conflicto entre generaciones y la alternancia continuidad-cambio social que genera y que constituye el motor de la creatividad. Para ello, se indaga en la etimología del concepto de ‘originalidad’, con el fin de encontrar los términos básicos con los que se asocia. Como se verá, concretamente lo hace con las palabras origen y originario u originante, que se fusionan (...) en el proceso creador, de manera que este establece una narrativa temporal en la que el pasado, el presente y el futuro quedan interrelacionados. Esta narrativa temporal se concreta en la sociedad y en la cultura modernas -especialmente, en el arte, la ciencia, la democracia y el capitalismo, cuatro de las creaciones más destacadas de la etapa-, diferenciándose la primera modernidad por su evolución desde la creatividad infantil o juvenil hacia la senil, y la segunda por la decadencia. Finalmente, el artículo concluye que la creatividad se define por la originalidad, porque construye una narración histórica y porque puede ayudar a eliminar la confusión del presente; que la infancia y la juventud de los creadores se vincula con el conflicto generacional; y que la primera modernidad constituye una etapa infantil o juvenil, mientras que la segunda se define por el declive generalizado físico, cultural y social. (shrink)

In this research work we approach to the knowledge of undiagnosed diseases. These diseases are framed within the so-called rare diseases, because they are not frequent. They generate a series of conditions in the lives of the affected people and in their social relationships. This is the result of the semiotic break between the biological and the social code. This situation can force people with these diseases to be out of the social structure, and they also can be reduced their (...) capacity to make decisions. For this reason, it is necessary to develop semiotics bridges that connect the codes we have talked about. (shrink)

RESUMEN Se exploran las relaciones entre hegemonía y filosofía de la praxis en A. Gramsci. Se examina la influencia de la filosofía hegeliana sobre estas nociones en los Cuadernos de la cárcel. Asimismo, se estudia la crítica a estas nociones a la luz del feminismo de la diferencia y del debate sobre hegemonía, universalidad y contingencia iniciado por E. Laclau, J. Butler y S. Žižek. Se concluye que concebir la hegemonía desde la perspectiva de la filosofía de la praxis (...) significa que la acción político-intelectual, según Gramsci, no solo implica la formación de una hegemonía alternativa, sino una crítica políticamente operante a la pretensión de universalidad del discurso hegemónico a partir de la exposición de su contingencia histórica. ABSTRACT The paper explores the relations between hegemony and the philosophy of praxis in A. Gramsci, and examines the influence of Hegelian philosophy on these notions as set forth in the Prison Notebooks. Likewise, it studies the critique of these notions from the perspective of difference feminism and of the debate over hegemony, universality, and contingency initiated by E. Laclau, J. Butler, and S. Žižek. The conclusion is that conceiving hegemony from the perspective of the philosophy of praxis means that, according to Gramsci, political-intellectual action implies not only the formation of an alternative hegemony, but also a politically operative critique of the claim to universality of hegemonic discourse, on the basis of the unveiling of its historical contingency. (shrink)

resumo Neste trabalho é analisada a estratégia da exposição de Fichte em seu escrito Sobre o conceito da Doutrina da Ciência e interpretada como indo de encontro a um determinado tipo do ceticismo moderno. Todavia, ao contrário da leitura proposta por Rockmore, que sustenta ser possível considerar toda a epistemologia fichteana dessa época como uma linha de argumentação de cunho pragmático e antifundacionista, defende-se a tese de que Fichte está comprometido desde o início com a tarefa de uma fundamentação última (...) de toda ciência a partir de um primeiro princípio. Esta fundamentação seria levada a cabo mediante uma demonstração indireta que pretende refutar de modo muito original objeções levantadas por Maimon, por Schulze e outros contra a filosofia transcendental de Kant. O mero fato de que Fichte não considerasse este último princípio como passível de demonstração direta não é suficiente para tachar sua estratégia de pragmática. palavras-chave Fichte; Filosofia Transcendental; Pragmatismo; Ceticismo; Fundacionismo. (shrink)

In this full review paper, the recent emerging trends in Computing Structures, Software Science, and System Applications have been reviewed and explored to address the recent topics and contributions in the era of the Software and Computing fields. This includes a set of rigorously reviewed world-class manuscripts addressing and detailing state-of-the-art, framework, implemented approaches and techniques research projects in the areas of Software Technology & Automation, Networking, Systems, Computing Sciences and Software Engineering, Big Data and E-learning. Based on this systematic (...) review, we have put some recommendations and suggestions for researchers, practitioners and scholars to improve their research quality in this area. (shrink)

This article highlights two possible unnoticed acrostics in Ovid's Metamorphoses concerning the predictions of Calchas and Helenus.

Interview with Juan. A. Negrete, annual prize 2014 to the promotion of the philosophy and the culture in Málaga. The award is extended to the network of blogs: Cavernisofía, Cavernética and Cavernisofíasegundaplanta.

In recent decades, there has been a proliferation among the scientific community of works that focus on Alan Turing’s contributions to the design and development of the modern computer. However, there are significant discrepancies among these studies, to such a point that some of them cast serious doubts on Alan Turing’s work with respect to today’s computer, and there are others that staunchly defend his leading role, as well as other studies that set out more well-balanced opinions. Faced with this (...) situation, the aim of this paper is to analyse the evidence existing today in order to be able to draw a conclusion about whether or not Turing anticipated the trivialisation of the modern computer memory and, likewise, if his universal a-machine is the precursor of the general-purpose computer so omnipresent today. As a result of our research, the authors conclude that Turing did indeed play a leading role in the appearance of the modern computer, although he was not the only one or the first in the field of Computing Science, albeit he was the most influential, both in scope and in depth. (shrink)

O presente artigo parte do princípio de que há uma relação intrínseca entre a metafísica e a teodkeia. A primeira é um sistema que oferece sentido, inteligibilidade, verdade e universalidade. O seu pressuposto fundamental é o de Parménides e o de Hegel, ou seja, a correspondência entre ser e pensamento, a racionalidade do real e a realidade do racional. Este é o ponto de partida da teologia natural grega, do teísmo cosmológico cristão, do teísmo antropológico moderno e das filosofias do (...) progresso dos últimos séculos. A teodiceia procura superar o último obstáculo que se opõe a esses sistemas, o mal na sua tripla dimensão de mal metafísico, físico e moral. O mal é impermeável à razão e sem sentido, ou seja, é aquilo que mais impede a transparência e a inteligibilidade do mundo. Começando por assumir esta proposta, o autor analisa finalmente a crise actual do sujeito e da metafísica, a crise pós-mo-derna da razão e dos sistemas universais. O novo contexto em que nos encontramos, o de uma metafísica débil, oferece novas oportunidades à proposta cristã, à impossibilidade da teodiceia como teoria especulativa e à possibilidade de uma resposta de sentido e comprometida com aquilo que é o maior dos sem-sentidos, o mal. /// There is an intrinsk relation between metaphysics and theodicy. The first one is a system which offers meaning, intelligibility, truth and universality. Its fundamental presupposition is the Parmenidian one and the Hegelian one, the correspondence between being and thought, the rationality of what is real and the reality of what is rational. This is the starting point of the Greek natural theology, of the Christian cosmologkal theism, of the modern anthropological theism and of the philosophies of progress of the last centuries. Theodicy tries to overcome the last obstacle whkh opposes to those systems, evil in its triple dimension of metaphysical, physical and moral evil. Evil is not rationable norfunctionable, it is what does not have meaning, what hinders the world's transparency and intelligibility. The author assumes this in order to finally analyse the crisis of the subject and of metaphysks, the postmodern crisis of reason and of universal systems. His claim is that this new context, the one of feeble metaphysks, offers new opportunities to the Christian proposal, whereby it asserts at the same time the impossibility of theodicy as a speculative theory and the possibility of a meaningful and committed answer to what is the biggest of all meaningless things, evil. /// Hay una relación intrínseca entre la metafísica y la teodicea. La primera es un sistema que ofrece sentido, inteligibilidad, verdad y universalidad. Su presupuesto fundamental es el parmenideo y hegeliano: la correspondencia entre ser y pensamiento, la racionalidad de lo real y la realidad de lo rational. Este es el punto de partida de la teología natural griega, del teísmo cosmológico cristiano, del teísmo antropológico moderno y de las filosofías del progreso de los dos últimos siglos. La teodicea busca superar el último obstáculo que se opone a esos sistemas, el mal en su triple dimensión de mal metafísico, físico y moral. El mal es lo no racionalizable, ni funcionalizable, lo que no tiene sentido, lo que impide la trasparencia e inteligibilidad del mundo. El autor asume este planteamiento, para analizar finalmente la crisis actual del sujeto y la metafísica, la crisis postmoderna de la razón y de los sistemas universales. El nuevo contexto, el de una metafísica débil, ofrece nuevas oportunidades al planteamiento cristiano, a la imposibilidad de la teodicea como teoría especulativa y a la posibilidad de una respuesta de sentido y comprometida con lo que es el mayor de los sin sentidos, el mal. (shrink)

Juan A. Nicolás, Department of Philosophy II, Universidad de Granada, Granada, Spain © 2010 Juan A. Nicolás Sociedad Española Leibniz has started the project ‘Leibniz en español’Leibniz in Spanish...

RESUMENLa tesis es, más bien, que la discusión del empirismo, la solución de ese reto empirista que separa el pensar del ser, forma parte de la altura histórica de la filosofía en el momento presente, es una exigencia suya. Si la filosofía comenzó buscando la unidad del ser, ha proseguido resquebrajándola; en particular distinguiendo el ser creado del increado, y luego distinguiendo el ser natural del personal, las cosas de las personas. Estas distinciones afectan de una manera muy particular a (...) las relaciones entre el ser y el pensar, y a su eventual unidad; éste es, por eso, el tema del empirismo, y de nuestro tiempo.PALABRAS CLAVESEMPIRISMO, SER, PENSARABSTRACTThe argument is that the discussion of empiricism is a requirement of philosophy at the present time, solving that challenge that separates thinking of being. If philosophy began seeking the unity of being, has continued dividing this unity; in particular distinguishing the uncreated and created being, and then distinguishing the natural and the personal being. These distinctions affect a particular the relationship between being and thinking, and his eventual drive way; it is, therefore, the issue of empiricism, and our time.KEY WORDSEMPIRICISM, BEING, THINK. (shrink)

O presente artigo trata da influência exercida pela filosofia kantiana na actualidade a partir da chamada crise da Modernidade ilustrada. Os autores começam por analisar o posicionamento original kantiano, incidindo especialmente na sua concepção do criticismo e do transcendentalismo. Esta análise é feita a partir da perspectiva da aberta pela Kritik der Urteilskraft enquanto marco do sistema da razão, capaz de incorporar a finitude da mesma. Seguidamente são analisadas a recepção e a transformação do pensamento kantiano a partir de duas (...) correntes filosóflcas actuais: o Racionalismo Crítico de Karl Popper e Hans Albert, e a Pragmática Transcendental da linguagem de Karl-Otto Apel. Em ambos os casos se compara o sen modo próprio de incorporar as noções de crítica e transcendentalidade com a concepção original de Kant. /// The article addresses the influence of Kantian philosophy in contemporary thought from the view point of the crisis of illustrated Modernity. The authors start by analyzing the original Kantian position, whereby particular attention is given to his conception of criticism and transcendentalism. This analysis is worked out from the perspective of the Kritik der Urteilskraft as a frame for the system of reason, able to incorporate the finitude of reason itself This is followed by a detailed analysis of the reception and the transformation of illustrated thinking performed by two contemporary philosophical schools: Critical Rationalism (Karl Popper and Hans Albert), and Transcendental Pragmatics of language (Karl-Otto Apel). The authors of the article compare in each case the adoption of the notions of critique and transcendentality with the original use that Kant himself makes of them. (shrink)

English summary: G.W. Leibniz's philosophy represents a fundamental chapter in the constitution of what we mean by modernity. Leibniz can be considered a source of inspiration for both the moment of the emergence of modernity as well as for the moment of the crisis of Enlightenment. Despite his influence on various authors, Leibniz does not let himself be identified with the core of Enlightenment thinking that was prevalent in the Western world in recent centuries. We are therefore faced with a (...) thinking that in its development depends neither on the enlightened modernity, nor on the principal alternative, hermeneutics. Thus, the span of Leibniz's thought ranges from the time before the Enlightenment through to post-hermeneutics. This volume presents a selection of articles from the "IV Congreso Internacional Leibniz: G. W. Leibniz entre la genesis y la crisis de la Modernidad" which was selected by the "Sociedad Espanola Leibniz" held in Granada. German, English, & French text. German description: Die Philosophie G. W. Leibniz stellt ein grundlegendes Kapitel fuer die Konstituierung dessen dar, was wir unter Modernitat verstehen. Leibniz kann als eine Inspirationsquelle sowohl im Moment der Entstehung der Modernitat als auch im Moment der Krise der Aufklarung verstanden werden. Trotz seines Einflusses auf verschiedene Autoren lasst sich Leibniz nicht mit dem Kern des aufklarerischen Denkens identifizieren, das in der westlichen Welt in den letzten Jahrhunderten vorherrschend war. Wir stehen also vor einem Denken, das in seinem Werdegang weder von der aufgeklarten Modernitat noch von deren hauptsachlicher Alternative, der Hermeneutik, abhangt. Somit spannt sich der Bogen des Denkens Leibniz von der Zeit vor der Aufklarung bis hin zur Post-Hermeneutik. Dieser Sammelband prasentiert eine Auswahl der Beitrage auf dem IV Congreso Internacional Leibniz: G. W. Leibniz entre la genesis y la crisis de la Modernidad, der von der Sociedad espanola Leibniz in Granada abgehalten wurde. Die Studien umfassen vier thematische Bereiche: Leibniz und die Entstehung der Modernitat, die Prinzipien der Philosophie und der Naturwissenschaften, die Sprachphilosophie und die Erkenntnistheorie, Ontologie und Theodizee. (shrink)

English summary: G.W. Leibniz's philosophy represents a fundamental chapter in the constitution of what we mean by modernity. Leibniz can be considered a source of inspiration for both the moment of the emergence of modernity as well as for the moment of the crisis of Enlightenment. Despite his influence on various authors, Leibniz does not let himself be identified with the core of Enlightenment thinking that was prevalent in the Western world in recent centuries. We are therefore faced with a (...) thinking that in its development depends neither on the enlightened modernity, nor on the principal alternative, hermeneutics. Thus, the span of Leibniz's thought ranges from the time before the Enlightenment through to post-hermeneutics. This volume presents a selection of articles from the "IV Congreso Internacional Leibniz: G. W. Leibniz entre la genesis y la crisis de la Modernidad" which was selected by the "Sociedad Espanola Leibniz" held in Granada. German, English, & French text. German description: Die Philosophie G. W. Leibniz stellt ein grundlegendes Kapitel fur die Konstituierung dessen dar, was wir unter Modernitat verstehen. Leibniz kann als eine Inspirationsquelle sowohl im Moment der Entstehung der Modernitat als auch im Moment der Krise der Aufklarung verstanden werden. Trotz seines Einflusses auf verschiedene Autoren lasst sich Leibniz nicht mit dem Kern des aufklarerischen Denkens identifizieren, das in der westlichen Welt in den letzten Jahrhunderten vorherrschend war. Wir stehen also vor einem Denken, das in seinem Werdegang weder von der aufgeklarten Modernitat noch von deren hauptsachlicher Alternative, der Hermeneutik, abhangt. Somit spannt sich der Bogen des Denkens Leibniz von der Zeit vor der Aufklarung bis hin zur Post-Hermeneutik. Dieser Sammelband prasentiert eine Auswahl der Beitrage auf dem IV Congreso Internacional Leibniz: G. W. Leibniz entre la genesis y la crisis de la Modernidad, der von der Sociedad espanola Leibniz in Granada abgehalten wurde. Die Studien umfassen vier thematische Bereiche: Leibniz und die Entstehung der Modernitat, die Prinzipien der Philosophie und der Naturwissenschaften, die Sprachphilosophie und die Erkenntnistheorie, Ontologie und Theodizee. (shrink)

On pose la question de la justification du principe de la raison suffisante dans la philosophic leibnizienne. On part de la portée universelle que Leibniz attribue au principe dans beaucoup de textes. Mais en même temps Leibniz montre aussi certains limites de ce principe qui empechent, au moins apparemment, son universalité. II s'agit des champs dont il n'est pas possible de rendre raison. Pour eviter cette paradoxe on applique le principe sur lui m& me. A partir de Tautoapplication du principe (...) on propose une fondamentarion du meme dans la ligne de la philosophic transcendantale. (shrink)

Turing was an exceptional mathematician with a peculiar and fascinating personality and yet he remains largely unknown. In fact, he might be considered the father of the von Neumann architecture computer and the pioneer of Artificial Intelligence. And all thanks to his machines; both those that Church called “Turing machines” and the a-, c-, o-, unorganized- and p-machines, which gave rise to evolutionary computations and genetic programming as well as connectionism and learning. This paper looks at all of these and (...) at why he is such an often overlooked and misunderstood figure. (shrink)

La pregunta por el hombre ha generado distintas respuestas. Las antropologías están ligadas a los códigos culturales y en éstos han sido determinantes las teologías. En esta breve reflexión se analizan las antropologías hebreas, griegas y cristianas, comparándolas y especificando sus aportaciones a la cultura occidental. Se concluye con algunas indicaciones sobre la discusión antropológica actual.

Chondrogenesis is a key process in skeletogenesis since endochondral ossification requires the formation of a cartilaginous template. Knowledge of molecular mechanisms regulating chondrogenesis is extremely valuable not only to understand many human disorders but also in regenerative medicine. Embryonic skeletogenesis is an excellent model to study this mechanism. Most cartilages share the cellular basis underlying chondrogenesis but the high heterogeneity in morphologies of the different skeletal elements appears to be generated by differential participation of a variety of chondrogenic signals. Here (...) we overview the regulatory factors responsible for chondrogenesis concluding that early chondrogenic signals for the digit cartilages differ from those implicated in the formation of other axial and appendicular skeletal components. BioEssays 29:725–737, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

La primera etapa de la formación de la filosofía de Levinas se expone en este texto: aquel que va de 1929 a 1947. Los dos libros principales de Levinas son estudiados en este trabajo: La Existencia del Existente y El Tiempo y el Otro. En este trabajo pretendo examinar la formación de la filosofía de Levinas: su emergencia desde la fenomenología husserliana y un incipiente personalismo, hasta la primera gran obra que nos presenta el pensamiento original de Levinas, que creo (...) que es El tiempo y el otro, que data del curso 1946-7. (shrink)

The human person looks wither inside towards her more intimate truth, or it omits that search and one forgets himself generously. Then it finds: noticing without getting to see, and also watching and supervising. It is the metalogic unfolding of the personal freedom: a gift that we accept and we give back looking for the divine acceptance.